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Merck

PRG2

proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)

同義詞:
BMPG, MBP, MBP1
物種:
UniProtKB ID:
基因 ID:
  • Human(5553) Summary: The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
  • Mouse(19074) proteoglycan 2, bone marrow
  • Rat(58826) proteoglycan 2, bone marrow
  • Horse(100062803) proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)

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Antibodies

產品編號
描述
物種活性
應用
嗜酸性粒细胞主要碱性蛋白抗体,克隆BMK13, clone BMK13, Chemicon®, from mouse,
物種活性
human
應用
ELISA
immunohistochemistry

western blot