跳轉至內容
Merck

PLOD2

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2

同義詞:
LH2, TLH
物種:
UniProtKB ID:
基因 ID:
  • Human(5352) Summary: The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(26432) procollagen lysine, 2-oxoglutarate 5-dioxygenase 2
  • Rat(300901) procollagen lysine, 2-oxoglutarate 5-dioxygenase 2
  • Zebrafish(100036767) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
  • Horse(100061030) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
  • chicken(424882) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
  • dog(485702) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
  • domestic cat(101085741) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
  • domestic guinea pig(100735218) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
  • naked mole-rat(101708679) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
  • cow(533642) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
  • sheep(101103613) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

產品編號
描述
物種活性
應用
Anti-PLOD2 antibody produced in rabbit, affinity isolated antibody,
物種活性
bovine, dog, horse, human, mouse, pig, rabbit, rat
應用
immunohistochemistry
western blot
Anti-PLOD2 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
物種活性
human
應用
immunofluorescence
western blot