PKM
pyruvate kinase, muscle
CTHBP, OIP3, PK3, PKM2, TCB, THBP1
Human PKM (5315), Mouse Pkm (18746), Rat Pkm (25630), cow PKM (512571), sheep PKM (101109180), Domestic Rabbit PKM (100008676), naked mole-rat Pkm (101721034), domestic guinea pig Pkm (100736056), Horse PKM (100063687), domestic cat PKM (101092521)
- Human(5315) Summary: This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011]
- Mouse(18746) pyruvate kinase, muscle
- Rat(25630) pyruvate kinase, muscle
- cow(512571) pyruvate kinase, muscle
- sheep(101109180) pyruvate kinase, muscle
- Domestic Rabbit(100008676) pyruvate kinase, muscle
- naked mole-rat(101721034) pyruvate kinase, muscle
- domestic guinea pig(100736056) pyruvate kinase, muscle
- Horse(100063687) pyruvate kinase, muscle
- domestic cat(101092521) pyruvate kinase, muscle
- dog(403874) pyruvate kinase, muscle
Custom & Knockdown Gene Products
siRNA
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shRNA
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Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Anti-PKM2 (C-terminal) antibody produced in rabbit, ~1.5 mg/mL, affinity isolated antibody,
human, mouse, rat
immunofluorescence
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot