PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
DCRC, DCRC-S, DSCR5, DSRC
Human PIGP (51227), Mouse Pigp (56176), Rat Pigp (288238), naked mole-rat Pigp (101721784), domestic guinea pig Pigp (100715662), cow PIGP (767951), Zebrafish pigp (325316), dog PIGP (478413), chicken PIGP (418517)
- Human(51227) Summary: This gene encodes an enzyme involved in the first step of glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. The encoded protein is a component of the GPI-N-acetylglucosaminyltransferase complex that catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). This gene is located in the Down Syndrome critical region on chromosome 21 and is a candidate for the pathogenesis of Down syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
- Mouse(56176) phosphatidylinositol glycan anchor biosynthesis, class P
- Rat(288238) phosphatidylinositol glycan anchor biosynthesis, class P
- naked mole-rat(101721784) phosphatidylinositol glycan anchor biosynthesis, class P
- domestic guinea pig(100715662) phosphatidylinositol glycan anchor biosynthesis, class P
- cow(767951) phosphatidylinositol glycan anchor biosynthesis, class P
- Zebrafish(325316) phosphatidylinositol glycan, class P
- dog(478413) phosphatidylinositol glycan anchor biosynthesis, class P
- chicken(418517) phosphatidylinositol glycan anchor biosynthesis, class P
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