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Merck

PDE1B

phosphodiesterase 1B, calmodulin-dependent

同義詞:
PDE1B1, PDES1B
物種:
UniProtKB ID:
基因 ID:
  • Human(5153) Summary: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
  • Mouse(18574) phosphodiesterase 1B, Ca2+-calmodulin dependent
  • Rat(29691) phosphodiesterase 1B, calmodulin-dependent
  • Domestic Rabbit(100341084) phosphodiesterase 1B, calmodulin-dependent
  • naked mole-rat(101718122) phosphodiesterase 1B, calmodulin-dependent
  • domestic guinea pig(100527959) phosphodiesterase 1B, Ca2+-calmodulin dependent
  • cow(281970) phosphodiesterase 1B, calmodulin-dependent
  • sheep(101118773) phosphodiesterase 1B, calmodulin-dependent
  • dog(100856025) phosphodiesterase 1B, calmodulin-dependent
  • Horse(100064711) phosphodiesterase 1B, calmodulin-dependent
  • domestic cat(101094608) phosphodiesterase 1B, calmodulin-dependent

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Small Molecule - Inhibitor

產品編號
描述
物種
8-Methoxymethyl-3-isobutyl-1-methylxanthine, ≥98%,
物種
human
长春西汀, ≥98%, solid,
物種
human
茶碱, anhydrous, ≥99%, powder,
物種
mouse, human, rat
咯利普兰, solid, ≥98% (HPLC),
物種
human, mouse, rat
双嘧达莫, United States Pharmacopeia (USP) Reference Standard,
物種
human