PARN
poly(A)-specific ribonuclease
同義詞:
DAN
物種:
Human PARN (5073), Mouse Parn (74108), Rat Parn (360464), sheep PARN (101112185), naked mole-rat Parn (101715275), Domestic Rabbit PARN (100351489), domestic guinea pig Parn (100732149), Zebrafish parn (791461), cow PARN (524155), chicken PARN (416423) ...更多
UniProtKB ID:
基因 ID:
- Human(5073) Summary: The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
- Mouse(74108) poly(A)-specific ribonuclease (deadenylation nuclease)
- Rat(360464) poly(A)-specific ribonuclease
- sheep(101112185) poly(A)-specific ribonuclease
- naked mole-rat(101715275) poly(A)-specific ribonuclease
- Domestic Rabbit(100351489) poly(A)-specific ribonuclease
- domestic guinea pig(100732149) poly(A)-specific ribonuclease
- Zebrafish(791461) poly(A)-specific ribonuclease (deadenylation nuclease)
- cow(524155) poly(A)-specific ribonuclease
- chicken(416423) poly(A)-specific ribonuclease
- domestic cat(101100021) poly(A)-specific ribonuclease
- dog(479839) poly(A)-specific ribonuclease
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Antibodies
產品編號
描述
物種活性
應用
Anti-PARN antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物種活性
human, mouse, rat
應用
immunofluorescence
western blot
western blot