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Merck

PAK7

p21 protein (Cdc42/Rac)-activated kinase 7

同義詞:
PAK5
物種:
UniProtKB ID:
基因 ID:
  • Human(57144) Summary: The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]
  • Mouse(241656) p21 protein (Cdc42/Rac)-activated kinase 7
  • Rat(311450) p21 protein (Cdc42/Rac)-activated kinase 7
  • Zebrafish(405898) p21(CDKN1A)-activated kinase 7
  • dog(485772) p21 protein (Cdc42/Rac)-activated kinase 7
  • chicken(416734) p21 protein (Cdc42/Rac)-activated kinase 7
  • Horse(100051415) p21 protein (Cdc42/Rac)-activated kinase 7
  • cow(513432) p21 protein (Cdc42/Rac)-activated kinase 7
  • domestic cat(101091011) p21 protein (Cdc42/Rac)-activated kinase 7
  • domestic guinea pig(100731594) p21 protein (Cdc42/Rac)-activated kinase 7
  • naked mole-rat(101697197) p21 protein (Cdc42/Rac)-activated kinase 7
  • sheep(101107882) p21 protein (Cdc42/Rac)-activated kinase 7

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Antibodies

產品編號
描述
物種活性
應用
Anti-PAK5 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物種活性
human
應用
ELISA
immunocytochemistry

western blot
Anti-phospho-PAK5/6 (pSer602/560) antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
western blot