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Merck

NSD1

nuclear receptor binding SET domain protein 1

同義詞:
ARA267, KMT3B, SOTOS, SOTOS1, STO
物種:
UniProtKB ID:
基因 ID:
  • Human(64324) Summary: This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(18193) nuclear receptor-binding SET-domain protein 1
  • Rat(306764) nuclear receptor binding SET domain protein 1
  • sheep(101120917) nuclear receptor binding SET domain protein 1
  • naked mole-rat(101698401) nuclear receptor binding SET domain protein 1
  • Domestic Rabbit(100355926) nuclear receptor binding SET domain protein 1
  • domestic guinea pig(100727598) nuclear receptor binding SET domain protein 1
  • chicken(416214) nuclear receptor binding SET domain protein 1
  • cow(540197) nuclear receptor binding SET domain protein 1
  • Horse(100058570) nuclear receptor binding SET domain protein 1
  • domestic cat(101100618) nuclear receptor binding SET domain protein 1
  • dog(489094) nuclear receptor binding SET domain protein 1

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Antibodies

產品編號
描述
物種活性
應用
Monoclonal Anti-NSD1 antibody produced in mouse, clone 1C12, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
western blot
Anti-NSD1, affinity isolated antibody,
物種活性
human
應用
immunohistochemistry
抗NSD1抗体,克隆1NW-1A10, ascites fluid, clone 1NW-1A10, from mouse,
物種活性
mouse, rat
應用
immunocytochemistry
immunofluorescence

immunohistochemistry

western blot