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Merck

NF2

neurofibromin 2 (merlin)

同義詞:
ACN, BANF, SCH
物種:
UniProtKB ID:
基因 ID:
  • Human(4771) Summary: This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts. [provided by RefSeq, Jul 2008]
  • Mouse(18016) neurofibromatosis 2
  • Rat(25744) neurofibromin 2 (merlin)
  • chicken(395158) neurofibromin 2 (bilateral acoustic neuroma)
  • dog(477535) neurofibromin 2 (merlin)
  • domestic cat(101087787) neurofibromin 2 (merlin)
  • cow(540479) neurofibromin 2 (merlin)
  • Horse(100058977) neurofibromin 2 (merlin)
  • Domestic Rabbit(100357691) neurofibromin 2 (merlin)
  • naked mole-rat(101706100) neurofibromin 2 (merlin)
  • domestic guinea pig(100715365) neurofibromin 2 (merlin)
  • sheep(101107995) neurofibromin 2 (merlin)

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Antibodies

產品編號
描述
物種活性
應用
抗-NF2 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物種活性
human, mouse, rat
應用
immunofluorescence
immunohistochemistry

western blot
Anti-Merlin (NF2) Antibody, clone 1C4, clone 1C4, from mouse,
物種活性
human, mouse, rat
應用
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-phospho-Merlin (pSer10) antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunohistochemistry

western blot