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Merck

MYC

v-myc avian myelocytomatosis viral oncogene homolog

同義詞:
MRTL, MYCC, bHLHe39, c-Myc
物種:
Human MYC (4609), Mouse Myc (17869), Rat Myc (24577), chicken MYC (420332), dog MYC (403924), domestic cat MYC (100379628), cow MYC (511077), domestic guinea pig Myc (100724557), Domestic Rabbit MYC (100327265), sheep MYC (443447)
UniProtKB ID:
P01106, A8WFE7, P01107, Q14026
基因 ID:
  • Human(4609) Summary: The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008]
  • Mouse(17869) myelocytomatosis oncogene
  • Rat(24577) myelocytomatosis oncogene
  • chicken(420332) v-myc myelocytomatosis viral oncogene homolog
  • dog(403924) v-myc myelocytomatosis viral oncogene homolog (avian)
  • domestic cat(100379628) v-myc myelocytomatosis viral oncogene homolog (avian)
  • cow(511077) v-myc myelocytomatosis viral oncogene homolog (avian)
  • domestic guinea pig(100724557) v-myc myelocytomatosis viral oncogene homolog (avian)
  • Domestic Rabbit(100327265) v-myc myelocytomatosis viral oncogene homolog (avian)
  • sheep(443447) v-myc myelocytomatosis viral oncogene homolog (avian)

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ELISA

產品編號
描述
物種
RAB1379
Human c-Myc ELISA, for serum, plasma and cell culture supernatants,
物種
human

Antibodies

產品編號
描述
物種活性
應用
M4439
Anti-c-Myc抗体，小鼠单克隆 小鼠抗, clone 9E10, purified from hybridoma cell culture,
物種活性
human
應用
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
05-724
抗Myc标签抗体，克隆4A6, clone 4A6, Upstate®, from mouse,
物種活性
human
應用
ChIP
immunocytochemistry
immunofluorescence
immunoprecipitation (IP)
western blot
C3956
抗-c-Myc 兔抗, ~0.5 mg/mL, affinity isolated antibody, buffered aqueous solution,
物種活性
human
應用
immunocytochemistry
immunofluorescence
immunoprecipitation (IP)
microarray
western blot
16-308
抗-Myc标签抗体，克隆9E10，Alexa Fluor™ 488偶联物, clone 9E10, Upstate®, from mouse,
物種活性
all
應用
immunocytochemistry
western blot
A7470
Anti-c-Myc 琼脂糖亲和凝胶 兔抗, affinity isolated antibody,
物種活性
human
應用
affinity chromatography
immunoprecipitation (IP)

Proteins

產品編號
描述
物種
SRP2089
C-myc, proto oncogene human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
物種
human

esiRNA

產品編號
描述
物種
EHU021051
MISSION® esiRNA, targeting human MYC,
物種
human