MSH6
mutS homolog 6
同義詞:
GTBP, GTMBP, HNPCC5, HSAP, p160
物種:
Human MSH6 (2956), Mouse Msh6 (17688), Zebrafish msh6 (260437), fruit fly Msh6 (39654), Thale Cress MSH6 (828147), chicken MSH6 (421291), cow MSH6 (540526), domestic cat MSH6 (101082303), dog MSH6 (474585), Domestic Rabbit MSH6 (100351645) ...更多
UniProtKB ID:
基因 ID:
- Human(2956) Summary: This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein of this gene combines with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene have been identified in individuals with hereditary nonpolyposis colon cancer (HNPCC) and endometrial cancer. [provided by RefSeq, Jul 2008]
- Mouse(17688) mutS homolog 6 (E. coli)
- Zebrafish(260437) mutS homolog 6 (E. coli)
- fruit fly(39654) CG7003 gene product from transcript CG7003-RA
- Thale Cress(828147) DNA mismatch repair protein MSH6
- chicken(421291) mutS homolog 6 (E. coli)
- cow(540526) mutS homolog 6 (E. coli)
- domestic cat(101082303) mutS homolog 6 (E. coli)
- dog(474585) mutS homolog 6 (E. coli)
- Domestic Rabbit(100351645) mutS homolog 6 (E. coli)
- naked mole-rat(101708261) mutS homolog 6 (E. coli)
- domestic guinea pig(100725043) mutS homolog 6 (E. coli)
- sheep(101107426) mutS homolog 6 (E. coli)
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Antibodies
產品編號
描述
物種活性
應用
Monoclonal Anti-MSH6 antibody produced in mouse, clone 1F2, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
immunofluorescence
proximity ligation assay
western blot
immunofluorescence
proximity ligation assay
western blot