MME
membrane metallo-endopeptidase
同義詞:
CALLA, CD10, NEP, SFE
物種:
Human MME (4311), Mouse Mme (17380), Rat Mme (24590), chicken MME (425031), dog MME (477120), cow MME (536741), Horse MME (100053541), domestic cat MME (101087516), sheep MME (101112618), domestic guinea pig Mme (100724320) ...更多
UniProtKB ID:
基因 ID:
- Human(4311) Summary: This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing. [provided by RefSeq, Jul 2008]
- Mouse(17380) membrane metallo endopeptidase
- Rat(24590) membrane metallo-endopeptidase
- chicken(425031) membrane metallo-endopeptidase
- dog(477120) membrane metallo-endopeptidase
- cow(536741) membrane metallo-endopeptidase
- Horse(100053541) membrane metallo-endopeptidase
- domestic cat(101087516) membrane metallo-endopeptidase
- sheep(101112618) membrane metallo-endopeptidase
- domestic guinea pig(100724320) membrane metallo-endopeptidase
- naked mole-rat(101715828) membrane metallo-endopeptidase
- Domestic Rabbit(100009251) membrane metallo-endopeptidase
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Antibodies
產品編號
描述
物種活性
應用
抗脑啡肽酶抗体（中性内肽酶，Nep）, serum, Chemicon®,
物種活性
human, mouse, rat
應用
immunohistochemistry
western blot
western blot
Monoclonal Anti-CD10 antibody produced in mouse, clone MEM-78, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
flow cytometry
ANTI-NEPRILYSIN(C-TERMINAL) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物種活性
human
應用
flow cytometry
immunohistochemistry
western blot
immunohistochemistry
western blot
Milli-Mark® Anti-CD10-FITC Antibody, clone SS2/36, clone SS2/36, Milli-Mark®, from mouse,
物種活性
human
應用
flow cytometry
Small Molecule - Inhibitor
Proteins
產品編號
描述
物種