跳轉至內容
Merck

MCM2

minichromosome maintenance complex component 2

同義詞:
BM28, CCNL1, CDCL1, D3S3194, MITOTIN, cdc19
物種:
UniProtKB ID:
基因 ID:
  • Human(4171) Summary: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012]
  • Mouse(17216) minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
  • Rat(312538) minichromosome maintenance complex component 2
  • domestic guinea pig(100722936) minichromosome maintenance complex component 2
  • naked mole-rat(101710978) minichromosome maintenance complex component 2
  • sheep(101116097) minichromosome maintenance complex component 2
  • Zebrafish(192338) MCM2 minichromosome maintenance deficient 2, mitotin (S. cerevisiae)
  • domestic cat(101090176) minichromosome maintenance complex component 2
  • dog(484622) minichromosome maintenance complex component 2
  • cow(510120) minichromosome maintenance complex component 2
  • chicken(416027) minichromosome maintenance complex component 2
  • Thale Cress(841056) minichromosome maintenance protein 2
  • fruit fly(40973) Minichromosome maintenance 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

產品編號
描述
物種活性
應用
Rabbit anti-Phospho MCM2 (S108) Antibody, Affinity Purified, ,
物種活性
human, mouse
應用
immunohistochemistry
western blot
Rabbit anti-MCM2 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
物種活性
human, mouse
應用
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-MCM2 antibody, Rabbit monoclonal, clone SP85, recombinant, expressed in proprietary host, affinity isolated antibody,
物種活性
bovine, dog, frog, human, mouse, rat
應用
flow cytometry
immunohistochemistry

western blot