MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
同義詞:
MARCH-I, RNF171
物種:
Human MARCH1 (55016), Mouse March1 (72925), Rat March1 (361135), chicken MARCH1 (422420), cow MARCH1 (617247), dog MARCH1 (612618), domestic cat MARCH1 (101098865), sheep MARCH1 (101106078), naked mole-rat March1 (101724772), domestic guinea pig March1 (100722498)
UniProtKB ID:
基因 ID:
- Human(55016) Summary: MARCH1 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH1 downregulates the surface expression of major histocompatibility complex (MHC) class II molecules (see MIM 142880) and other glycoproteins by directing them to the late endosomal/lysosomal compartment (Bartee et al., 2004 [PubMed 14722266]
- Mouse(72925) membrane-associated ring finger (C3HC4) 1
- Rat(361135) membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
- chicken(422420) membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
- cow(617247) membrane-associated ring finger (C3HC4) 1
- dog(612618) membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
- domestic cat(101098865) membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
- sheep(101106078) membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
- naked mole-rat(101724772) membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
- domestic guinea pig(100722498) membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
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Antibodies
產品編號
描述
物種活性
應用
Monoclonal Anti-MARCH1 antibody produced in mouse, clone 3D2, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
Anti-MARCH1 antibody produced in rabbit, affinity isolated antibody,
物種活性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
應用
western blot