跳轉至內容
Merck

MAP2K6

mitogen-activated protein kinase kinase 6

同義詞:
MAPKK6, MEK6, MKK6, PRKMK6, SAPKK-3, SAPKK3
物種:
Human MAP2K6 (5608), Mouse Map2k6 (26399), Rat Map2k6 (114495), domestic guinea pig Map2k6 (100731419), naked mole-rat Map2k6 (101703028), Domestic Rabbit MAP2K6 (100355230), sheep MAP2K6 (101115047), Zebrafish map2k6 (65239), cow MAP2K6 (286883), Horse MAP2K6 (100053056) ...更多
UniProtKB ID:
P52564
基因 ID:
  • Human(5608) Summary: This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. [provided by RefSeq, Jul 2008]
  • Mouse(26399) mitogen-activated protein kinase kinase 6
  • Rat(114495) mitogen-activated protein kinase kinase 6
  • domestic guinea pig(100731419) mitogen-activated protein kinase kinase 6
  • naked mole-rat(101703028) mitogen-activated protein kinase kinase 6
  • Domestic Rabbit(100355230) mitogen-activated protein kinase kinase 6
  • sheep(101115047) mitogen-activated protein kinase kinase 6
  • Zebrafish(65239) mitogen-activated protein kinase kinase 6
  • cow(286883) mitogen-activated protein kinase kinase 6
  • Horse(100053056) mitogen-activated protein kinase kinase 6
  • domestic cat(101089813) mitogen-activated protein kinase kinase 6
  • chicken(417445) mitogen-activated protein kinase kinase 6
  • dog(480454) mitogen-activated protein kinase kinase 6

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

產品編號
描述
物種活性
應用
15-109
SAPK Pathway Explorer Antibody Minipack, Upstate®,
物種活性
應用
SAB4502412
Anti-MKK6 antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunohistochemistry
western blot

Small Molecule - Inhibitor

產品編號
描述
物種
P215
PD 98,059, solid,
物種
human

Proteins

產品編號
描述
物種
SRP0372
MKK6 active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥80% (SDS-PAGE),
物種
human
M5814
MKK6/SKK3, active human, ≥80% (SDS-PAGE), recombinant, expressed in E. coli, Maltose binding protein tagged, buffered aqueous solution,
物種
human
14-304
MKK6/SKK3 Protein, inactive, 50 g, Unactive, recombinant human MKK6, amino acids 4-end, fused at the N-terminus to a Mal-E tag, for use in Kinase Assays.,
物種
human