LPIN1
lipin 1
PAP1
Human LPIN1 (23175), Mouse Lpin1 (14245), Rat Lpin1 (313977), Zebrafish lpin1 (799099), dog LPIN1 (475670), Horse LPIN1 (100072273), cow LPIN1 (537224), domestic cat LPIN1 (101085623), chicken LPIN1 (421945), sheep LPIN1 (101120647) ...更多
- Human(23175) Summary: This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined. [provided by RefSeq, May 2012]
- Mouse(14245) lipin 1
- Rat(313977) lipin 1
- Zebrafish(799099) lipin 1
- dog(475670) lipin 1
- Horse(100072273) lipin 1
- cow(537224) lipin 1
- domestic cat(101085623) lipin 1
- chicken(421945) lipin 1
- sheep(101120647) lipin 1
- domestic guinea pig(100718634) lipin 1
- Domestic Rabbit(100346262) lipin 1
- naked mole-rat(101721483) lipin 1
Custom & Knockdown Gene Products
siRNA
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shRNA
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Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Anti-LPIN1 antibody produced in rabbit, affinity isolated antibody,
dog, horse, human, mouse, rabbit, rat
immunohistochemistry
western blot
western blot
Monoclonal Anti-LPIN1, (C-terminal) antibody produced in mouse, clone 3D9, purified immunoglobulin, buffered aqueous solution,
human
ELISA
western blot
western blot