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Merck

LPHN1

latrophilin 1

同義詞:
CIRL1, CL1, LEC2
物種:
UniProtKB ID:
基因 ID:
  • Human(22859) Summary: This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Oct 2008]
  • Mouse(330814) latrophilin 1
  • Rat(65096) latrophilin 1
  • domestic cat(101091175) latrophilin 1
  • cow(788252) latrophilin 1
  • dog(610349) latrophilin 1
  • naked mole-rat(101708219) latrophilin 1
  • domestic guinea pig(100712781) latrophilin 1
  • sheep(101118356) latrophilin 1

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Antibodies

產品編號
描述
物種活性
應用
Anti-LPHN1 antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunofluorescence