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Merck

LMNA

lamin A/C

同義詞:
CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, LDP1, LFP, LGMD1B, LMN1, LMNC, LMNL1, PRO1
物種:
Human LMNA (4000), Mouse Lmna (16905), Rat Lmna (60374), Zebrafish lmna (195815), cow LMNA (404144), Horse LMNA (100057663), domestic cat LMNA (101086199), dog LMNA (480124), chicken LMNA (415464), domestic guinea pig Lmna (100735212) ...更多
UniProtKB ID:
P02545, B4DI32, D3DVB0, E7EUI9, P02546, Q5TCJ2, Q5TCJ3, Q969I8
基因 ID:
  • Human(4000) Summary: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq, Apr 2012]
  • Mouse(16905) lamin A
  • Rat(60374) lamin A/C
  • Zebrafish(195815) lamin A
  • cow(404144) lamin A/C
  • Horse(100057663) lamin A/C
  • domestic cat(101086199) lamin A/C
  • dog(480124) lamin A/C
  • chicken(415464) lamin A/C
  • domestic guinea pig(100735212) lamin A/C
  • naked mole-rat(101704567) lamin A/C
  • sheep(101107924) lamin A/C

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Antibodies

產品編號
描述
物種活性
應用
05-1231
早老蛋白抗体，克隆13A4, clone 13A4, Upstate®, from mouse,
物種活性
human
應用
ELISA
immunocytochemistry
immunoprecipitation (IP)
western blot
MABT345
抗-Prelamin-A抗体，克隆7G11, clone 7G11, from rat,
物種活性
mouse
應用
immunofluorescence
western blot
SAB4200272
Anti-Progerin antibody, Mouse monoclonal, clone 13A4, purified from hybridoma cell culture,
物種活性
human
應用
immunofluorescence
immunoprecipitation (IP)
western blot
MAB3540
Anti-Lamin A Antibody, CT, a.a. 598-611, clone 133A2, clone 133A2, Chemicon®, from mouse,
物種活性
bovine, canine, human, mouse, rat
應用
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
MABT1341
Anti-Lamin A/C Antibody, clone 4C11, clone 4C11, from mouse,
物種活性
syrian hamster, human, monkey, mouse, rat
應用
ChIP
immunofluorescence
immunoprecipitation (IP)
western blot

esiRNA

產品編號
描述
物種
EHU063791
MISSION® esiRNA, targeting human LMNA,
物種
human