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Merck

KLC1

kinesin light chain 1

同義詞:
KLC, KNS2, KNS2A
物種:
UniProtKB ID:
基因 ID:
  • Human(3831) Summary: Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named 'kinesin 2', this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature and/or biological validity of most of these variants have not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(16593) kinesin light chain 1
  • Rat(171041) kinesin light chain 1
  • chicken(423484) kinesin light chain 1
  • cow(508999) kinesin light chain 1
  • Horse(100055290) kinesin light chain 1
  • domestic cat(101099130) kinesin light chain 1
  • dog(480446) kinesin light chain 1
  • sheep(101102677) kinesin light chain 1
  • domestic guinea pig(100736081) kinesin light chain 1
  • naked mole-rat(101710626) kinesin light chain 1

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Antibodies

產品編號
描述
物種活性
應用
Anti-Kinesin Antibody, light chain, clone L2, clone L2, Chemicon®, from mouse,
物種活性
mammals
應用
ELISA
immunoprecipitation (IP)

radioimmunoassay

western blot