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Merck

KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

同義詞:
C-Kit, CD117, PBT, SCFR
物種:
Human KIT (3815), Mouse Kit (16590), Rat Kit (64030), chicken KIT (378783), domestic cat KIT (493766), cow KIT (280832), Horse KIT (100009704), dog KIT (403811), Goat KIT (100861386), sheep KIT (780504) ...更多
UniProtKB ID:
P10721, B5A956, D5LXN2, D5M931, F5H8F8, Q6IQ28, Q99662, Q9UM99
基因 ID:
  • Human(3815) Summary: This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(16590) kit oncogene
  • Rat(64030) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • chicken(378783) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • domestic cat(493766) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • cow(280832) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • Horse(100009704) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • dog(403811) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • Goat(100861386) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • sheep(780504) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • Domestic Rabbit(100327263) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • domestic guinea pig(100726397) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • naked mole-rat(101726400) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Antibodies

產品編號
描述
物種活性
應用
117R-1
CD117, c-kit (YR145) Rabbit Monoclonal Primary Antibody, ,
物種活性
應用
07-806
抗磷酸化-c-Kit （Tyr568/ Tyr570）抗体, Upstate®, from rabbit,
物種活性
human
應用
western blot
SAB4501648
Anti-C-KIT antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
western blot
CBL1360
Anti-CD117 Antibody, clone ACK2, clone ACK2, Chemicon®, from rat,
物種活性
mouse
應用
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
western blot
SAB4700750
Monoclonal Anti-CD117 antibody produced in mouse, clone 104D2, purified immunoglobulin, buffered aqueous solution,
物種活性
bovine, human, nonhuman primates
應用
flow cytometry
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)

Small Molecule - Inhibitor

產品編號
描述
物種
CDS022173
伊马替尼, ,
物種
human
PZ0012
Sunitinib malate, ≥98% (HPLC),
物種
human
CDS023580
帕唑帕尼, ,
物種
human
SML2589
达沙替尼, ≥98% (HPLC),
物種
human
CDS023389
达沙替尼, ,
物種
human

Proteins

產品編號
描述
物種
14-559-M
c-Kit Protein, active, 10 µg, Active, N-terminal GST tagged, recombinant, human Kit, amino acids 544-end, for use in Kinase Assays.,
物種
human
14-611-M
c-Kit (D816V) Protein, active, 10 µg, Active, N-terminal GST tagged, recombinant human c-Kit, amino acids 544-end containing the D816V mutation, for use in Kinase Assays.,
物種
human
14-726-M
c-Kit (D816H) Protein, active, 10 µg, Active, N-terminal GST tagged, recombinant, human c-Kit, amino acids 544-end containing the mutation D816H, for use in Kinase Assays.,
物種
human
C0499
c-KIT (544-end, V654A), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物種
human
14-730-M
c-Kit (V560G) Protein, active, 10 µg, Active, N-terminal GST tagged recombinant human c-Kit, amino acids 544 -end, containing the V560G mutation, found in patients with gastrointestinal stromal tumours. For use in Kinase Assays.,
物種
human