IL5RA
interleukin 5 receptor, alpha
同義詞:
CD125, CDw125, HSIL5R3, IL5R
物種:
Human IL5RA (3568), Mouse Il5ra (16192), Rat Il5ra (114103), chicken IL5RA (771801), domestic cat IL5RA (101099031), cow IL5RA (615848), dog IL5RA (476553), domestic guinea pig Il5ra (100379257), naked mole-rat Il5ra (101701153), sheep IL5RA (101111837)
UniProtKB ID:
基因 ID:
- Human(3568) Summary: The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. [provided by RefSeq, Jul 2011]
- Mouse(16192) interleukin 5 receptor, alpha
- Rat(114103) interleukin 5 receptor, alpha
- chicken(771801) interleukin 5 receptor, alpha
- domestic cat(101099031) interleukin 5 receptor, alpha
- cow(615848) interleukin 5 receptor, alpha
- dog(476553) interleukin 5 receptor, alpha
- domestic guinea pig(100379257) interleukin 5 receptor, alpha
- naked mole-rat(101701153) interleukin 5 receptor, alpha
- sheep(101111837) interleukin 5 receptor, alpha
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