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Merck

IL18BP

interleukin 18 binding protein

同義詞:
IL18BPa
物種:
UniProtKB ID:
基因 ID:
  • Human(10068) Summary: The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
  • Mouse(16068) interleukin 18 binding protein
  • Rat(84388) interleukin 18 binding protein
  • domestic guinea pig(100714819) interleukin 18 binding protein
  • naked mole-rat(101721919) interleukin 18 binding protein
  • sheep(101118983) interleukin 18 binding protein
  • cow(617470) interleukin 18 binding protein
  • domestic cat(101096599) interleukin 18 binding protein
  • dog(476818) interleukin 18 binding protein

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Antibodies

產品編號
描述
物種活性
應用
Monoclonal Anti-IL18BP antibody produced in mouse, clone 2A9, purified immunoglobulin, buffered aqueous solution,
物種活性
human, mouse, rat
應用
ELISA
western blot
Anti-IL18BP antibody produced in rabbit, affinity isolated antibody,
物種活性
human
應用
western blot

Proteins

產品編號
描述
物種
IL18BP human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
物種
human