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Merck

IDH2

isocitrate dehydrogenase 2 (NADP+), mitochondrial

同義詞:
D2HGA2, ICD-M, IDH, IDHM, IDP, IDPM, mNADP-IDH
物種:
UniProtKB ID:
基因 ID:
  • Human(3418) Summary: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. [provided by RefSeq, Jul 2008]
  • Mouse(269951) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • Rat(361596) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • Zebrafish(386951) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • cow(327669) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • domestic cat(101082315) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • dog(479043) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • chicken(431056) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • Thale Cress(816218) Isocitrate dehydrogenase [NAD] regulatory subunit 2
  • domestic guinea pig(100726681) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • naked mole-rat(101708667) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • sheep(101102843) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • Domestic Rabbit(100340796) isocitrate dehydrogenase 2 (NADP+), mitochondrial

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Antibodies

Product Number
描述
物種活性
應用
Anti-IDH2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物種活性
bovine, canine, human, mouse, rat
應用
ELISA
immunohistochemistry

western blot
Monoclonal Anti-IDH2 antibody produced in mouse, clone 5F11, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
immunohistochemistry

western blot
Anti-IDH2 antibody produced in rabbit, affinity isolated antibody,
物種活性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
應用
western blot
Anti-IDH2 antibody produced in rabbit, ,
物種活性
human, mouse, rat
應用
immunohistochemistry
western blot
Anti-IDH2 antibody produced in rabbit, ,
物種活性
human, mouse, rat
應用
immunohistochemistry
western blot

Kits

Product Number
描述
物種
IDH 活性检测试剂盒, sufficient for 100 colorimetric tests,
物種
mouse, rat, human

Proteins

Product Number
描述
物種
IDH2, FLAG® -Tag, recombinant, expressed in baculovirus infected Sf9 cells,
物種
human

esiRNA

Product Number
描述
物種
MISSION® esiRNA, targeting mouse Idh2,
物種
mouse
MISSION® esiRNA, targeting human IDH2,
物種
human