HP
haptoglobin
同義詞:
BP, HP2ALPHA2, HPA1S
物種:
Human HP (3240), Mouse Hp (15439), Rat Hp (24464), Zebrafish hp (566096), fruit fly hp (251278), dog HP (479668), cow HP (280692), domestic cat HP (100144610), domestic guinea pig Hp (100721435), naked mole-rat Hp (101705743) ...更多
UniProtKB ID:
基因 ID:
- Human(3240) Summary: This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(15439) haptoglobin
- Rat(24464) haptoglobin
- Zebrafish(566096) haptoglobin
- fruit fly(251278) humped
- dog(479668) haptoglobin
- cow(280692) haptoglobin
- domestic cat(100144610) haptoglobin
- domestic guinea pig(100721435) haptoglobin
- naked mole-rat(101705743) haptoglobin
- sheep(101102413) haptoglobin
- Domestic Rabbit(100008816) haptoglobin
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Antibodies
產品編號
描述
物種活性
應用
Anti-Haptoglobin antibody produced in rabbit, IgG fraction of antiserum, lyophilized powder,
物種活性
human
應用
ELISA
Anti-Haptoglobin antibody, Mouse monoclonal, clone HG-36, purified from hybridoma cell culture,
物種活性
human
應用
ELISA
dot blot
immunoprecipitation (IP)
western blot
dot blot
immunoprecipitation (IP)
western blot
Anti-HP antibody produced in rabbit, affinity isolated antibody,
物種活性
human
應用
immunohistochemistry
western blot
western blot
Proteins
產品編號
描述
物種