HLA-E
major histocompatibility complex, class I, E
EA1.2, EA2.1, HLA-6.2, MHC, QA1
- Human(3133) Summary: HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. [provided by RefSeq, Jul 2008]
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Antibodies
Monoclonal Anti-HLA-E antibody produced in mouse, clone MEM-E/08, purified immunoglobulin, buffered aqueous solution,
human
flow cytometry
Monoclonal Anti-HLA-E-Biotin antibody produced in mouse, clone MEM-E/07, purified immunoglobulin, buffered aqueous solution,
human
flow cytometry
抗HLA I类抗原抗体,克隆W6 / 32, clone W6/32, from mouse,
human
affinity binding assay
affinity chromatography
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
neutralization
affinity chromatography
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
neutralization