HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
同義詞:
DFNB39, F-TCF, HGFB, HPTA, SF
物種:
Human HGF (3082), Mouse Hgf (15234), Rat Hgf (24446), domestic guinea pig Hgf (100730730), naked mole-rat Hgf (101707056), sheep HGF (443075), Domestic Rabbit HGF (100316908), chicken HGF (395941), cow HGF (282879), domestic cat HGF (493705)
UniProtKB ID:
基因 ID:
- Human(3082) Summary: Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- Mouse(15234) hepatocyte growth factor
- Rat(24446) hepatocyte growth factor
- domestic guinea pig(100730730) hepatocyte growth factor (hepapoietin A; scatter factor)
- naked mole-rat(101707056) hepatocyte growth factor (hepapoietin A; scatter factor)
- sheep(443075) hepatocyte growth factor (hepapoietin A; scatter factor)
- Domestic Rabbit(100316908) hepatocyte growth factor (hepapoietin A; scatter factor)
- chicken(395941) hepatocyte growth factor (hepapoietin A; scatter factor)
- cow(282879) hepatocyte growth factor (hepapoietin A; scatter factor)
- domestic cat(493705) hepatocyte growth factor (hepapoietin A; scatter factor)
- dog(403441) hepatocyte growth factor (hepapoietin A; scatter factor)
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ELISA
Antibodies
產品編號
描述
物種活性
應用
Anti-HGF antibody produced in rabbit, affinity isolated antibody,
物種活性
bovine, dog, horse, human, mouse, pig, rabbit, rat
應用
western blot
Anti-HGF (ab2) antibody produced in rabbit, affinity isolated antibody,
物種活性
bovine, dog, horse, human, mouse, pig, rabbit, rat, sheep
應用
immunohistochemistry
western blot
western blot
Anti-HGF antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物種活性
human, mouse
應用
proximity ligation assay
western blot
western blot
Anti-c-Met Antibody, clone seeMet 13, clone seeMet 13, from mouse,
物種活性
human
應用
flow cytometry
immunocytochemistry
immunoprecipitation (IP)
inhibition assay
immunocytochemistry
immunoprecipitation (IP)
inhibition assay
Anti-HGF (ab1) antibody produced in rabbit, affinity isolated antibody,
物種活性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
應用
immunohistochemistry
western blot
western blot
Proteins
產品編號
描述
物種
肝细胞生长因子 人, HGF, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture,
物種
human
肝细胞生长因子 人, HGF, recombinant, expressed in Baculovirus infected High-5 cells, suitable for cell culture,
物種
human
HGF mouse, recombinant, expressed in Hi-5 Insect cells, ≥95% (SDS-PAGE), ≥95% (HPLC),
物種
mouse