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Merck

HDAC8

histone deacetylase 8

同義詞:
CDLS5, HD8, HDACL1, MRXS6, RPD3, WTS
物種:
UniProtKB ID:
基因 ID:
  • Human(55869) Summary: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
  • Mouse(70315) histone deacetylase 8
  • Rat(363481) histone deacetylase 8
  • Zebrafish(406740) histone deacetylase 8
  • cow(540666) histone deacetylase 8
  • domestic cat(101096383) histone deacetylase 8
  • dog(480957) histone deacetylase 8
  • chicken(422182) histone deacetylase 8
  • domestic guinea pig(100721893) histone deacetylase 8
  • naked mole-rat(101697998) histone deacetylase 8
  • sheep(101110121) histone deacetylase 8

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Antibodies

產品編號
描述
物種活性
應用
Monoclonal Anti-Histone Deacetylase 8 (HDAC8) antibody produced in mouse, 2.0-2.5 mg/mL, clone HDAC8-48, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
microarray

western blot
Monoclonal Anti-HDAC8 antibody produced in mouse, clone 2F4, purified immunoglobulin, buffered aqueous solution,
物種活性
human, mouse, rat
應用
ELISA
immunofluorescence

western blot
Anti-HDAC8 Antibody, serum, Upstate®,
物種活性
human, mouse
應用
immunoprecipitation (IP)
western blot
Anti-HDAC8 antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunohistochemistry

western blot
Anti-phospho-HDAC8 (pSer39) antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunohistochemistry

western blot

Small Molecule - Inhibitor

產品編號
描述
物種
曲古抑菌素A, ≥98% (HPLC), from Streptomyces sp.,
物種
human, mouse, rat
罗咪酯肽, ≥98% (HPLC),
物種
human
CI−994, ≥98% (HPLC), powder,
物種
human