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Merck

HDAC6

histone deacetylase 6

同義詞:
HD6
物種:
Human HDAC6 (10013), Mouse Hdac6 (15185), Rat Hdac6 (84581), Zebrafish hdac6 (565482), domestic cat HDAC6 (101084086), cow HDAC6 (513602), dog HDAC6 (480907), fruit fly HDAC6 (32461), domestic guinea pig Hdac6 (100717988), naked mole-rat Hdac6 (101708442)
UniProtKB ID:
Q9UBN7, O94975, Q6NT75, Q7L3E5, Q96CY0
基因 ID:
  • Human(10013) Summary: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq, Jul 2008]
  • Mouse(15185) histone deacetylase 6
  • Rat(84581) histone deacetylase 6
  • Zebrafish(565482) histone deacetylase 6
  • domestic cat(101084086) histone deacetylase 6
  • cow(513602) histone deacetylase 6
  • dog(480907) histone deacetylase 6
  • fruit fly(32461) CG6170 gene product from transcript CG6170-RA
  • domestic guinea pig(100717988) histone deacetylase 6
  • naked mole-rat(101708442) histone deacetylase 6
  • sheep(101109245) histone deacetylase 6

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Antibodies

產品編號
描述
物種活性
應用
WH0010013M1
Monoclonal Anti-HDAC6 antibody produced in mouse, clone 1E2, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
western blot
AV31451
Anti-HDAC6 antibody produced in rabbit, affinity isolated antibody,
物種活性
dog, horse, human, pig, rabbit
應用
ChIP
immunohistochemistry
western blot
07-732
抗-HDAC6抗体，CT, Upstate®, from rabbit,
物種活性
human, mouse
應用
immunoprecipitation (IP)
western blot
SAB4504190
Anti-phospho-HDAC6 (pSer22) antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunofluorescence
immunohistochemistry
western blot
SAB1404771
Monoclonal Anti-HDAC6 antibody produced in mouse, clone 3A6, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
immunofluorescence
western blot

Small Molecule - Inhibitor

產品編號
描述
物種
SML0061
SAHA, ≥98% (HPLC),
物種
human
T8552
曲古抑菌素A, ≥98% (HPLC), from Streptomyces sp.,
物種
human, mouse, rat
SML1175
罗咪酯肽, ≥98% (HPLC),
物種
human
C0621
CI−994, ≥98% (HPLC), powder,
物種
human

Proteins

產品編號
描述
物種
SRP0108
HDAC-6 human, recombinant, expressed in baculovirus infected insect cells, ≥80% (SDS-PAGE),
物種
human