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Merck

HDAC4

histone deacetylase 4

同義詞:
AHO3, BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA
物種:
UniProtKB ID:
基因 ID:
  • Human(9759) Summary: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008]
  • Mouse(208727) histone deacetylase 4
  • Rat(363287) histone deacetylase 4
  • Zebrafish(568877) histone deacetylase 4
  • chicken(374207) histone deacetylase 4
  • dog(607662) histone deacetylase 4
  • cow(517559) histone deacetylase 4
  • domestic cat(101093384) histone deacetylase 4
  • fruit fly(32278) CG1770 gene product from transcript CG1770-RG
  • domestic guinea pig(100713301) histone deacetylase 4
  • naked mole-rat(101696612) histone deacetylase 4
  • sheep(101108012) histone deacetylase 4

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Antibodies

產品編號
描述
物種活性
應用
Anti-HDAC4 (Ab-632) antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
immunofluorescence
western blot
Anti-phospho-HDAC4 (pSer632) antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
western blot
Anti-HDAC4 Antibody, serum, from rabbit,
物種活性
human
應用
ChIP
immunocytochemistry

immunoprecipitation (IP)

western blot
Anti-Histone Deacetylase 4 (HDAC4) (ML-19) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物種活性
human, mouse, rat
應用
immunofluorescence
immunoprecipitation (IP)

microarray

western blot
Anti-Histone Deacetylase 4 (HDAC4) (DM-15) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物種活性
human, mouse, rat
應用
immunofluorescence
immunoprecipitation (IP)

microarray

western blot

Small Molecule - Inhibitor

產品編號
描述
物種
曲古抑菌素A, ≥98% (HPLC), from Streptomyces sp.,
物種
human, mouse, rat
罗咪酯肽, ≥98% (HPLC),
物種
human
CI−994, ≥98% (HPLC), powder,
物種
human

Proteins

產品編號
描述
物種
HDAC-4 human, recombinant, expressed in baculovirus infected insect cells, ≥50% (SDS-PAGE),
物種
human