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Merck

HARS2

histidyl-tRNA synthetase 2, mitochondrial

同義詞:
HARSL, HARSR, HO3, PRLTS2
物種:
Human HARS2 (23438), Mouse Hars2 (70791), Rat Hars2 (307491), chicken HARS2 (768802), domestic cat HARS2 (101098429), cow HARS2 (615182), dog HARS2 (478035), domestic guinea pig Hars2 (100730771), naked mole-rat Hars2 (101713772), sheep HARS2 (101121599)
UniProtKB ID:
P49590
基因 ID:
  • Human(23438) Summary: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is an enzyme belonging to the class II family of aminoacyl-tRNA synthetases. Functioning in the synthesis of histidyl-transfer RNA, the enzyme plays an accessory role in the regulation of protein biosynthesis. The gene is located in a head-to-head orientation with HARS on chromosome five, where the homologous genes likely share a bidirectional promoter. Mutations in this gene are associated with the pathogenesis of Perrault syndrome, which involves ovarian dysgenesis and sensorineural hearing loss. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
  • Mouse(70791) histidyl-tRNA synthetase 2, mitochondrial (putative)
  • Rat(307491) histidyl-tRNA synthetase 2, mitochondrial
  • chicken(768802) histidyl-tRNA synthetase 2, mitochondrial (putative)
  • domestic cat(101098429) histidyl-tRNA synthetase 2, mitochondrial
  • cow(615182) histidyl-tRNA synthetase 2, mitochondrial (putative)
  • dog(478035) histidyl-tRNA synthetase 2, mitochondrial (putative)
  • domestic guinea pig(100730771) histidyl-tRNA synthetase 2, mitochondrial
  • naked mole-rat(101713772) histidyl-tRNA synthetase 2, mitochondrial
  • sheep(101121599) histidyl-tRNA synthetase 2, mitochondrial

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