GRIN2C
glutamate receptor, ionotropic, N-methyl D-aspartate 2C
同義詞:
GluN2C, NMDAR2C, NR2C
物種:
Human GRIN2C (2905), Mouse Grin2c (14813), Rat Grin2c (24411), sheep GRIN2C (101102915), domestic guinea pig Grin2c (100721967), naked mole-rat Grin2c (101698922), chicken GRIN2C (431090), dog GRIN2C (483302), cow GRIN2C (535158), domestic cat GRIN2C (101091740)
UniProtKB ID:
基因 ID:
- Human(2905) Summary: This gene encodes a subunit of the N-methyl-D-aspartate (NMDA) receptor, which is a subtype of ionotropic glutamate receptor. NMDA receptors are found in the central nervous system, are permeable to cations and have an important role in physiological processes such as learning, memory, and synaptic development. The receptor is a tetramer of different subunits (typically heterodimer of subunit 1 with one or more of subunits 2A-D), forming a channel that is permeable to calcium, potassium, and sodium, and whose properties are determined by subunit composition. Alterations in the subunit composition of the receptor are associated with pathophysiological conditions such as Parkinson's disease, Alzheimer's disease, depression, and schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
- Mouse(14813) glutamate receptor, ionotropic, NMDA2C (epsilon 3)
- Rat(24411) glutamate receptor, ionotropic, N-methyl D-aspartate 2C
- sheep(101102915) glutamate receptor, ionotropic, N-methyl D-aspartate 2C
- domestic guinea pig(100721967) glutamate receptor, ionotropic, N-methyl D-aspartate 2C
- naked mole-rat(101698922) glutamate receptor, ionotropic, N-methyl D-aspartate 2C
- chicken(431090) glutamate receptor, ionotropic, N-methyl D-aspartate 2C
- dog(483302) glutamate receptor, ionotropic, N-methyl D-aspartate 2C
- cow(535158) glutamate receptor, ionotropic, N-methyl D-aspartate 2C
- domestic cat(101091740) glutamate receptor, ionotropic, N-methyl D-aspartate 2C
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Small Molecule - Agonist
Small Molecule - Allosteric Modulator
產品編號
描述
物種
盐酸氯胺酮标准液 盐酸盐 溶液, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
物種
human
Small Molecule - Antagonist
Antibodies
產品編號
描述
物種活性
應用
Anti-NMDAR2C Antibody, also recognizes NMDAR2A and 2B, Chemicon®, from rabbit,
物種活性
rat
應用
immunoprecipitation (IP)
western blot
western blot
抗-谷氨酸受体NMDAR2C（NR2C） 兔抗, affinity isolated antibody, lyophilized powder,
物種活性
human, mouse, rat
應用
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot