GLRX2
glutaredoxin 2
同義詞:
CGI-133, GRX2
物種:
Human GLRX2 (51022), Mouse Glrx2 (69367), Rat Glrx2 (114022), Zebrafish glrx2 (436677), chicken GLRX2 (424357), dog GLRX2 (478956), domestic cat GLRX2 (101091421), cow GLRX2 (513762), domestic guinea pig Glrx2 (100714233), naked mole-rat Glrx2 (101697695)
UniProtKB ID:
基因 ID:
- Human(51022) Summary: The protein encoded by this gene is a member of the glutaredoxin family of proteins, which maintain cellular thiol homeostasis. These proteins are thiol-disulfide oxidoreductases that use a glutathione-binding site and one or two active cysteines in their active site. This gene undergoes alternative splicing to produce multiple isoforms, one of which is ubiquitously expressed and localizes to mitochondria, where it functions in mitochondrial redox homeostasis and is important for the protection against and recovery from oxidative stress. Other isoforms, which have more restrictive expression patterns, show cytosolic and nuclear localization, and are thought to function in cellular differentiation and transformation, possibly with a role in tumor progression. [provided by RefSeq, Aug 2011]
- Mouse(69367) glutaredoxin 2 (thioltransferase)
- Rat(114022) glutaredoxin 2
- Zebrafish(436677) glutaredoxin 2
- chicken(424357) glutaredoxin 2
- dog(478956) glutaredoxin 2
- domestic cat(101091421) glutaredoxin 2
- cow(513762) glutaredoxin 2
- domestic guinea pig(100714233) glutaredoxin 2
- naked mole-rat(101697695) glutaredoxin 2
- sheep(100135692) glutaredoxin 2
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Antibodies
Product Number
描述
物種活性
應用
Monoclonal Anti-GLRX2 antibody produced in mouse, clone 3E9, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
western blot
western blot