GCDH

glutaryl-CoA dehydrogenase

同義詞:

ACAD5, GCD

物種:

UniProtKB ID:

基因 ID:

Human(2639) Summary: The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Mutations in this gene result in the metabolic disorder glutaric aciduria type 1, which is also known as glutaric acidemia type I. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 12. [provided by RefSeq, Mar 2013]
Mouse(270076) glutaryl-Coenzyme A dehydrogenase
Rat(364975) glutaryl-CoA dehydrogenase
Zebrafish(393860) glutaryl-Coenzyme A dehydrogenase
cow(506310) glutaryl-CoA dehydrogenase
Horse(100063310) glutaryl-CoA dehydrogenase
domestic cat(101086880) glutaryl-CoA dehydrogenase
chicken(771098) glutaryl-CoA dehydrogenase
dog(476696) glutaryl-CoA dehydrogenase
sheep(101122190) glutaryl-CoA dehydrogenase
Domestic Rabbit(100343376) glutaryl-CoA dehydrogenase
naked mole-rat(101718348) glutaryl-CoA dehydrogenase
domestic guinea pig(100714939) glutaryl-CoA dehydrogenase

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Product Number

描述

物種活性

應用

Anti-GCDH antibody produced in rabbit, IgG fraction of antiserum,

物種活性

dog, horse, human, mouse, pig, rabbit, rat

應用

immunohistochemistry
western blot