FZD8
frizzled family receptor 8
同義詞:
FZ-8, hFZ8
物種:
Human FZD8 (8325), Mouse Fzd8 (14370), Rat Fzd8 (364754), chicken FZD8 (374059), domestic cat FZD8 (101101229), cow FZD8 (616913), naked mole-rat Fzd8 (101712115), domestic guinea pig Fzd8 (100719503)
UniProtKB ID:
基因 ID:
- Human(8325) Summary: This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008]
- Mouse(14370) frizzled homolog 8 (Drosophila)
- Rat(364754) frizzled family receptor 8
- chicken(374059) frizzled homolog 8 (Drosophila)
- domestic cat(101101229) frizzled family receptor 8
- cow(616913) frizzled family receptor 8
- naked mole-rat(101712115) frizzled family receptor 8
- domestic guinea pig(100719503) frizzled family receptor 8
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