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Merck

FLNA

filamin A, alpha

同義詞:
ABP-280, ABPX, CSBS, CVD1, FLN, FLN-A, FLN1, FMD, MNS, NHBP, OPD, OPD1, OPD2, XLVD, XMVD
物種:
UniProtKB ID:
基因 ID:
  • Human(2316) Summary: The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009]
  • Mouse(192176) filamin, alpha
  • Rat(293860) filamin A, alpha
  • Zebrafish(562529) filamin A, alpha (actin binding protein 280)
  • cow(281165) filamin A, alpha
  • domestic cat(101082637) filamin A, alpha
  • Zebrafish(100534866) filamin A, alpha
  • dog(481084) filamin A, alpha
  • chicken(395261) filamin A, alpha
  • sheep(101120390) filamin A, alpha
  • Domestic Rabbit(100328754) filamin A, alpha
  • naked mole-rat(101702004) filamin A, alpha
  • domestic guinea pig(100725162) filamin A, alpha

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Antibodies

Product Number
描述
物種活性
應用
抗纤维蛋白A抗体,克隆TI10, ascites fluid, clone TI10, Chemicon®,
物種活性
bovine, human
應用
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-Filamin antibody,Mouse monoclonal, clone PM6/317, purified from hybridoma cell culture,
物種活性
bovine, canine, hamster, human, monkey
應用
immunofluorescence
western blot
Anti-Filamin A antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunohistochemistry

western blot
Rabbit anti-Filamin A Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
物種活性
human, mouse
應用
immunohistochemistry
immunoprecipitation (IP)

western blot