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EGFR

epidermal growth factor receptor

同義詞:

ERBB, ERBB1, HER1, PIG61, mENA

物種:

Human EGFR (1956), Mouse Egfr (13649), Rat Egfr (24329), fruit fly Egfr (37455), cow EGFR (407217), Horse EGFR (100067755), domestic cat EGFR (100510799), dog EGFR (404306), chicken EGFR (396494), domestic guinea pig Egfr (100725363) ...更多

UniProtKB ID:

P00533, O00688, O00732, P06268, Q14225, Q68GS5, Q92795, Q9BZS2

基因 ID:

Human(1956) Summary: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
Mouse(13649) epidermal growth factor receptor
Rat(24329) epidermal growth factor receptor
fruit fly(37455) Epidermal growth factor receptor
cow(407217) epidermal growth factor receptor
Horse(100067755) epidermal growth factor receptor
domestic cat(100510799) epidermal growth factor receptor
dog(404306) epidermal growth factor receptor
chicken(396494) epidermal growth factor receptor
domestic guinea pig(100725363) epidermal growth factor receptor
naked mole-rat(101723771) epidermal growth factor receptor
sheep(780479) epidermal growth factor receptor

產品 (87)
同儕審查論文 (10,820)

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ELISA

產品編號

描述

物種

人EGFR/ ErbB1 ELISA试剂盒, for serum, plasma, cell culture supernatants and urine,

物種

human

基于细胞的磷酸化EGFR ELISA采样器套件, for detecting phospho-egfr(pTyr⁸⁴⁵), phospho-egfr(pTyr⁹⁹²), phospho-egfr(pTyr¹⁰⁶⁸) and phospho-egfr in cultured cell lines,

物種

human

Small Molecule - Antagonist

產品編號

描述

物種

Tyrphostin AG 1478（酪氨酸激酶抑制剂AG 1478）, ≥98%,

物種

human, mouse

SU 5416, ≥98% (HPLC),

物種

human, mouse

染料木黄酮, synthetic, ≥98% (HPLC), powder,

物種

mouse, human, rat

染料木黄酮, from Glycine max (soybean), ~98% (HPLC),

物種

mouse, human, rat

Antibodies

產品編號

描述

物種活性

應用

Anti-EGFRvIII Antibody, clone DH8.3, clone DH8.3, from mouse,

物種活性

human

應用

ELISA
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
western blot

Anti-EGFR Antibody, clone LA22, clone LA22, Upstate^®, from mouse,

物種活性

human

應用

immunocytochemistry
immunoprecipitation (IP)
western blot

抗-dEGF受体，细胞外结构域抗体，小鼠单克隆, clone C-273, purified from hybridoma cell culture,

物種活性

drosophila

應用

ELISA
immunohistochemistry
western blot

抗-EGFR抗体，中和，克隆LA1, clone LA1, Upstate^®, from mouse,

物種活性

human

應用

immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
neutralization
western blot

抗-表皮生长因子受体单克隆抗体小鼠抗, clone F4, ascites fluid,

物種活性

human

應用

ELISA
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot

Small Molecule - Inhibitor

產品編號

描述

物種

吉非替尼, ≥98% (HPLC),

物種

human

厄洛替尼盐酸盐, ,

物種

human

DAPH, ≥98% (HPLC), solid,

物種

human

Tyrphostin 1, ≥98%,

物種

human

PKI-166, ≥98% (HPLC),

物種

human

Proteins

產品編號

描述

物種

Epidermal Growth Factor Receptor human, lyophilized powder, ≥15,000 units/mg protein (Bradford),

物種

human

EGFR Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),

物種

human

EGFR/ErbB1 human, recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE),

物種

human

EGFR (T790M L858R) Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),

物種

human

EGF-receptor human, recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,

物種

human