DSP
desmoplakin
同義詞:
DP, DPI, DPII
物種:
Human DSP (1832), Mouse Dsp (109620), Rat Dsp (306871), fruit fly dsp (45846), cow DSP (514360), Horse DSP (100061514), chicken DSP (420869), domestic cat DSP (101098382), dog DSP (488207), domestic guinea pig Dsp (100721053) ...更多
UniProtKB ID:
基因 ID:
- Human(1832) Summary: Desmosomes are intercellular junctions that tightly link adjacent cells. Desmoplakin is an obligate component of functional desmosomes that anchors intermediate filaments to desmosomal plaques. The N-terminus of desmoplakin is required for localization to the desmosome and interacts with the N-terminal region of plakophilin 1 and plakoglobin. The C-terminus of desmoplakin binds with intermediate filaments. In the mid-region of desmoplakin, a coiled-coiled rod domain is responsible for homodimerization. Mutations in this gene are the cause of several cardiomyopathies and keratodermas as well as the autoimmune disease paraneoplastic pemphigus. [provided by RefSeq, Jul 2008]
- Mouse(109620) desmoplakin
- Rat(306871) desmoplakin
- fruit fly(45846) dispersed
- cow(514360) desmoplakin
- Horse(100061514) desmoplakin
- chicken(420869) desmoplakin
- domestic cat(101098382) desmoplakin
- dog(488207) desmoplakin
- domestic guinea pig(100721053) desmoplakin
- naked mole-rat(101708187) desmoplakin
- sheep(101119169) desmoplakin
- Domestic Rabbit(100354434) desmoplakin
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Antibodies
產品編號
描述
物種活性
應用
Anti-Desmoplakin 1& 2 Antibody, clone DP2.15, clone DP2.15, Chemicon®, from mouse,
物種活性
bovine, chicken, human, mouse, rat
應用
immunocytochemistry
immunofluorescence
western blot
immunofluorescence
western blot