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Merck

DDC

dopa decarboxylase (aromatic L-amino acid decarboxylase)

同義詞:
AADC
物種:
UniProtKB ID:
基因 ID:
  • Human(1644) Summary: The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2011]
  • Mouse(13195) dopa decarboxylase
  • Rat(24311) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • domestic guinea pig(100135516) dopa decarboxylase
  • naked mole-rat(101697555) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • sheep(101106765) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • Zebrafish(406651) dopa decarboxylase
  • chicken(420947) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • fruit fly(35190) Dopa decarboxylase
  • dog(606852) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • cow(280762) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • Horse(100052557) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • domestic cat(101082989) dopa decarboxylase (aromatic L-amino acid decarboxylase)

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Antibodies

產品編號
描述
物種活性
應用
Anti-Dopa Decarboxylase Antibody, Chemicon®, from rabbit,
物種活性
canine, human, sheep
應用
western blot
Monoclonal Anti-DDC antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2962, purified immunoglobulin, buffered aqueous glycerol solution,
物種活性
human, mouse, rat
應用
immunohistochemistry
western blot
Anti-DDC antibody produced in rabbit, affinity isolated antibody,
物種活性
guinea pig, human, mouse, rat
應用
western blot
Monoclonal Anti-DOPA Decarboxylase (DDC) antibody produced in mouse, clone DDC-109, ascites fluid,
物種活性
bovine, canine, guinea pig, human, monkey, rabbit, rat, sheep
應用
ELISA
immunocytochemistry

immunoprecipitation (IP)

microarray

western blot

Small Molecule - Inhibitor

產品編號
描述
物種
多巴丝肼 盐酸盐, ≥98% (HPLC), solid,
物種
human
卡比多巴, Pharmaceutical Secondary Standard; Certified Reference Material,
物種
human
(S)-3-(3,4-二羟基苯基)-2-肼基-2-甲基丙酸 一水合物, United States Pharmacopeia (USP) Reference Standard,
物種
human
S-(−)-Carbidopa, ≥98% (TLC), powder,
物種
human
多巴丝肼 盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物種
human