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Merck

DCTN2

dynactin 2 (p50)

同義詞:
DCTN50, DYNAMITIN, RBP50
物種:
UniProtKB ID:
基因 ID:
  • Human(10540) Summary: This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2012]
  • Mouse(69654) dynactin 2
  • Rat(299850) dynactin 2 (p50)
  • Zebrafish(394141) dynactin 2 (p50)
  • cow(527201) dynactin 2 (p50)
  • Horse(100050464) dynactin 2 (p50)
  • domestic cat(101093950) dynactin 2 (p50)
  • dog(474415) dynactin 2 (p50)
  • chicken(395587) dynactin 2 (p50)
  • naked mole-rat(101713049) dynactin 2 (p50)
  • domestic guinea pig(100721002) dynactin 2 (p50)
  • sheep(101119807) dynactin 2 (p50)
  • Domestic Rabbit(100339187) dynactin 2 (p50)

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Antibodies

產品編號
描述
物種活性
應用
Monoclonal Anti-DCTN2 antibody produced in mouse, clone 2G7, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
immunofluorescence

western blot