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Merck

CHRNA3

cholinergic receptor, nicotinic, alpha 3 (neuronal)

同義詞:
LNCR2, NACHRA3, PAOD2
物種:
UniProtKB ID:
基因 ID:
  • Human(1136) Summary: This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009]
  • Mouse(110834) cholinergic receptor, nicotinic, alpha polypeptide 3
  • Rat(25101) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • Zebrafish(568467) cholinergic receptor, nicotinic, alpha 3
  • dog(482111) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • domestic cat(100037403) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • cow(282702) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • chicken(386578) cholinergic receptor, nicotinic, alpha 3
  • naked mole-rat(101701279) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • domestic guinea pig(100730977) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • sheep(101123239) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • Domestic Rabbit(100342666) cholinergic receptor, nicotinic, alpha 3 (neuronal)

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Small Molecule - Agonist

產品編號
描述
物種
(±)-尼古丁, ≥99% (TLC), liquid,
物種
human, rat
卡巴胆碱, ≥98% (titration), crystalline,
物種
human, mouse, rat
Tropisetron, solid, ≥98% (HPLC),
物種
rat, human
(−)-尼古丁 溶液, 1.0 mg/mL, analytical standard, for drug analysis,
物種
human, mouse, rat
(−)-尼古丁, ≥99% (GC), liquid,
物種
human, mouse, rat

Small Molecule - Antagonist

產品編號
描述
物種
金雀花碱, ≥99%, powder,
物種
rat
(±)-尼古丁, ≥99% (TLC), liquid,
物種
human, rat
卡巴胆碱, ≥98% (titration), crystalline,
物種
human, mouse, rat
美加明 盐酸盐, ,
物種
human
Tropisetron, solid, ≥98% (HPLC),
物種
rat, human

Antibodies

產品編號
描述
物種活性
應用
Anti-CHRNA3 antibody produced in rabbit, affinity isolated antibody,
物種活性
dog, human, rabbit
應用
western blot
Monoclonal Anti-Nicotinic Acetylcholine Receptor (α1, α3, α5 Subunits) antibody produced in rat, clone mAb 35, purified immunoglobulin, buffered aqueous solution,
物種活性
chicken, eel, human
應用
immunohistochemistry

Small Molecule - Blocker

產品編號
描述
物種
四乙基氯化铵, ≥98% (titration),
物種
human
溴化已烷双胺, ,
物種
human
氯化六甲铵, solid (hygroscopic),
物種
human
犬尿喹啉酸, ≥98%,
物種
rat, human