CHRNA2
cholinergic receptor, nicotinic, alpha 2 (neuronal)
同義詞:
物種:
Human CHRNA2 (1135), Mouse Chrna2 (110902), Rat Chrna2 (170945), chicken CHRNA2 (395607), cow CHRNA2 (531838), domestic cat CHRNA2 (101092104), dog CHRNA2 (486101), sheep CHRNA2 (101107330), domestic guinea pig Chrna2 (100734964), naked mole-rat Chrna2 (101714975)
UniProtKB ID:
基因 ID:
- Human(1135) Summary: Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement of alpha and beta subunits to create distinct muscle and neuronal receptors. Neuronal receptors are found throughout the peripheral and central nervous system where they are involved in fast synaptic transmission. This gene encodes an alpha subunit that is widely expressed in the brain. The proposed structure for nAChR subunits is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. Mutations in this gene cause autosomal dominant nocturnal frontal lobe epilepsy type 4. Single nucleotide polymorphisms (SNPs) in this gene have been associated with nicotine dependence. [provided by RefSeq, Nov 2009]
- Mouse(110902) cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal)
- Rat(170945) cholinergic receptor, nicotinic, alpha 2 (neuronal)
- chicken(395607) cholinergic receptor, nicotinic, alpha 2 (neuronal)
- cow(531838) cholinergic receptor, nicotinic, alpha 2 (neuronal)
- domestic cat(101092104) cholinergic receptor, nicotinic, alpha 2 (neuronal)
- dog(486101) cholinergic receptor, nicotinic, alpha 2 (neuronal)
- sheep(101107330) cholinergic receptor, nicotinic, alpha 2 (neuronal)
- domestic guinea pig(100734964) cholinergic receptor, nicotinic, alpha 2 (neuronal)
- naked mole-rat(101714975) cholinergic receptor, nicotinic, alpha 2 (neuronal)
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Small Molecule - Agonist
產品編號
描述
物種
Small Molecule - Antagonist
Antibodies
產品編號
描述
物種活性
應用
Anti-CHRNA2 antibody produced in rabbit, affinity isolated antibody,
物種活性
human
應用
immunohistochemistry
western blot
western blot
Anti-CHRNA2 Antibody, clone 5B2.1, clone 5B2.1, from mouse,
物種活性
human
應用
immunohistochemistry
western blot
western blot