CDK2
cyclin-dependent kinase 2
同義詞:
p33(CDK2)
物種:
Human CDK2 (1017), Mouse Cdk2 (12566), Rat Cdk2 (362817), Zebrafish cdk2 (406715), cow CDK2 (519217), chicken CDK2 (100529062), dog CDK2 (606931), domestic cat CDK2 (101093368), domestic guinea pig Cdk2 (100714324), naked mole-rat Cdk2 (101725353) ...更多
UniProtKB ID:
基因 ID:
- Human(1017) Summary: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq, Jul 2008]
- Mouse(12566) cyclin-dependent kinase 2
- Rat(362817) cyclin dependent kinase 2
- Zebrafish(406715) cyclin-dependent kinase 2
- cow(519217) cyclin-dependent kinase 2
- chicken(100529062) cyclin-dependent kinase 2
- dog(606931) cyclin-dependent kinase 2
- domestic cat(101093368) cyclin-dependent kinase 2
- domestic guinea pig(100714324) cyclin-dependent kinase 2
- naked mole-rat(101725353) cyclin-dependent kinase 2
- Goat(100860751) cyclin-dependent kinase 2
- sheep(100216433) cyclin-dependent kinase 2
- Domestic Rabbit(100134865) cyclin-dependent kinase 2
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Antibodies
產品編號
描述
物種活性
應用
Anti-phospho-CDK2 (pThr160) antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
immunohistochemistry
western blot
western blot
Anti-phospho-CDK1/CDC2 (pThr14) antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
western blot
Anti-Cdk2 Antibody, clone AN4.3, clone AN4.3, Upstate®, from mouse,
物種活性
xenopus, human, mouse
應用
immunoprecipitation (IP)
western blot
western blot
抗-磷酸化-CDK1/CDC2 (pThr14) 兔抗, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-CDK2 antibody produced in rabbit, IgG fraction of antiserum,
物種活性
bovine, goat, human, mouse, rabbit, rat, sheep
應用
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Proteins
產品編號
描述
物種
p27 Protein complex, activated, 10 µg, Activated complex of three (3) full length, recombinant human proteins: p27, Cyclin E1, & CDK2. Phosphorylated in vitro using CDK2/Cyclin E1. For use in Enzyme Assays. Behaves as a substrate in ubiquitin assays.,
物種
human
Cdk1/cyclin B蛋白，活性，10 µg, Active, C-terminal His6-tagged human full length Cdk1 & N-terminal GST-tagged human full length Cyclin B, for use in Kinase Assays.,
物種
human
Cdk2/Cyclin E蛋白，活性，10 µg, Active complex of recombinant full length human Cdk2 containing a C-terminal His6-tag & recombinant full-length human Cyclin E containing an N-terminal GST-tag. For use in Kinase Assays.,
物種
human
CDK2/Cyclin A2, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物種
human
CDK2/CyclinE1，活性，GST 标记 人, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物種
human