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Merck

CDC25A

cell division cycle 25A

同義詞:
CDC25A2
物種:
UniProtKB ID:
基因 ID:
  • Human(993) Summary: CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(12530) cell division cycle 25A
  • Rat(171102) cell division cycle 25A
  • chicken(420375) cell division cycle 25 homolog A (S. pombe)
  • cow(520188) cell division cycle 25 homolog A (S. pombe)
  • Horse(100064223) cell division cycle 25 homolog A (S. pombe)
  • domestic cat(101098445) cell division cycle 25 homolog A (S. pombe)
  • dog(484780) cell division cycle 25 homolog A (S. pombe)
  • sheep(101113178) cell division cycle 25 homolog A (S. pombe)
  • domestic guinea pig(100721008) cell division cycle 25A
  • naked mole-rat(101699133) cell division cycle 25A

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Antibodies

產品編號
描述
物種活性
應用
Monoclonal Anti-CDC25A antibody produced in mouse, clone 3D5, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
proximity ligation assay

western blot

Small Molecule - Inhibitor

產品編號
描述
物種
NSC 95397, ≥97% (HPLC),
物種
human