CD53
CD53 molecule
同義詞:
MOX44, TSPAN25
物種:
Human CD53 (963), Mouse Cd53 (12508), Rat Cd53 (24251), naked mole-rat Cd53 (101719625), domestic guinea pig Cd53 (100735881), sheep CD53 (101112271), domestic cat CD53 (101084381), cow CD53 (505040), Horse CD53 (100058745), dog CD53 (610454)
UniProtKB ID:
基因 ID:
- Human(963) Summary: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
- Mouse(12508) CD53 antigen
- Rat(24251) Cd53 molecule
- naked mole-rat(101719625) CD53 molecule
- domestic guinea pig(100735881) CD53 molecule
- sheep(101112271) CD53 molecule
- domestic cat(101084381) CD53 molecule
- cow(505040) CD53 molecule
- Horse(100058745) CD53 molecule
- dog(610454) CD53 molecule
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