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Merck

CCR5

chemokine (C-C motif) receptor 5 (gene/pseudogene)

同義詞:
CC-CKR-5, CCCKR5, CCR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22
物種:
Human CCR5 (1234), Mouse Ccr5 (12774), Rat Ccr5 (117029), chicken CCR5 (420695), dog CCR5 (484789), domestic cat CCR5 (493769), cow CCR5 (497017), Horse CCR5 (100048935), sheep CCR5 (101117453), Domestic Rabbit CCR5 (100101579) ...更多
UniProtKB ID:
P51681, O14692, O14693, O14695, O14696, O14697, O14698, O14699
基因 ID:
  • Human(1234) Summary: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(12774) chemokine (C-C motif) receptor 5
  • Rat(117029) chemokine (C-C motif) receptor 5
  • chicken(420695) chemokine (C-C motif) receptor 5
  • dog(484789) chemokine (C-C motif) receptor 5
  • domestic cat(493769) chemokine (C-C motif) receptor 5
  • cow(497017) chemokine (C-C motif) receptor 5
  • Horse(100048935) chemokine (C-C motif) receptor 5
  • sheep(101117453) chemokine (C-C motif) receptor 5
  • Domestic Rabbit(100101579) chemokine (C-C motif) receptor 5
  • naked mole-rat(101723738) chemokine (C-C motif) receptor 5
  • domestic guinea pig(100716672) chemokine (C-C motif) receptor 5

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Small Molecule - Antagonist

產品編號
描述
物種
PZ0002
马拉韦罗, ≥98% (HPLC),
物種
human

Antibodies

產品編號
描述
物種活性
應用
AB1889
Anti-C-C Chemokine Receptor 5 Antibody, NT, Chemicon®, from rabbit,
物種活性
human
應用
western blot
PRS1112
Anti-CCR5 antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
物種活性
human
應用
ELISA
immunohistochemistry
western blot
SAB2108100
Anti-CCR5 antibody produced in rabbit, affinity isolated antibody,
物種活性
human, pig
應用
western blot