CCDC88A
coiled-coil domain containing 88A
同義詞:
APE, GIRDIN, GIV, GRDN, HkRP1, KIAA1212
物種:
Human CCDC88A (55704), Mouse Ccdc88a (108686), Rat Ccdc88a (305605), chicken CCDC88A (421210), domestic cat CCDC88A (101096803), cow CCDC88A (533248), Horse CCDC88A (100052471), dog CCDC88A (481375), domestic guinea pig Ccdc88a (100714383), naked mole-rat Ccdc88a (101708183) ...更多
UniProtKB ID:
基因 ID:
- Human(55704) Summary: This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
- Mouse(108686) coiled coil domain containing 88A
- Rat(305605) coiled coil domain containing 88A
- chicken(421210) coiled-coil domain containing 88A
- domestic cat(101096803) coiled-coil domain containing 88A
- cow(533248) coiled-coil domain containing 88A
- Horse(100052471) coiled-coil domain containing 88A
- dog(481375) coiled-coil domain containing 88A
- domestic guinea pig(100714383) coiled-coil domain containing 88A
- naked mole-rat(101708183) coiled-coil domain containing 88A
- sheep(101122010) coiled-coil domain containing 88A
- Domestic Rabbit(100346692) coiled-coil domain containing 88A
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Antibodies
產品編號
描述
物種活性
應用
Anti-phospho-Girdin (pSer1417) antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse
應用
immunohistochemistry