跳轉至內容
Merck

CBX3

chromobox homolog 3

同義詞:
HECH, HP1-GAMMA, HP1Hs-gamma
物種:
Human CBX3 (11335), Mouse Cbx3 (12417), Rat Cbx3 (297093), naked mole-rat Cbx3 (101714000), domestic guinea pig Cbx3 (100714020), sheep CBX3 (101106931), chicken CBX3 (395355), dog CBX3 (482015), cow CBX3 (539788), domestic cat CBX3 (101099363)
UniProtKB ID:
Q13185, Q96CD7, Q99409, Q9BVS3, Q9P0Z6
基因 ID:
  • Human(11335) Summary: At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011]
  • Mouse(12417) chromobox 3
  • Rat(297093) chromobox homolog 3
  • naked mole-rat(101714000) chromobox homolog 3
  • domestic guinea pig(100714020) chromobox homolog 3
  • sheep(101106931) chromobox homolog 3
  • chicken(395355) chromobox homolog 3
  • dog(482015) chromobox homolog 3
  • cow(539788) chromobox homolog 3
  • domestic cat(101099363) chromobox homolog 3

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
描述
物種活性
應用
05-690
抗-HP1γ 抗体，克隆42s2, clone 42s2, Upstate®, from mouse,
物種活性
human, mouse
應用
ChIP
immunohistochemistry
western blot
PLA0160
Rabbit anti-CBX3 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
物種活性
human
應用
immunohistochemistry
immunoprecipitation (IP)
MABE656
抗-HP1γ抗体，克隆14D3.1, clone 14D3.1, from mouse,
物種活性
human, mouse, nonhuman primates, rat
應用
immunocytochemistry
western blot
07-972
Anti-phospho-HP1 γ (Ser83) Antibody, Upstate®, from rabbit,
物種活性
human
應用
western blot
WH0011335M1
Monoclonal Anti-CBX3 antibody produced in mouse, clone 1G12-1D9, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
immunofluorescence
western blot