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Merck

CAMKK2

calcium/calmodulin-dependent protein kinase kinase 2, beta

同義詞:
CAMKK, CAMKKB
物種:
UniProtKB ID:
基因 ID:
  • Human(10645) Summary: The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases. [provided by RefSeq, Jul 2012]
  • Mouse(207565) calcium/calmodulin-dependent protein kinase kinase 2, beta
  • Rat(83506) calcium/calmodulin-dependent protein kinase kinase 2, beta
  • naked mole-rat(101723556) calcium/calmodulin-dependent protein kinase kinase 2, beta
  • domestic guinea pig(100716041) calcium/calmodulin-dependent protein kinase kinase 2, beta
  • sheep(101103267) calcium/calmodulin-dependent protein kinase kinase 2, beta
  • chicken(396405) calcium/calmodulin-dependent protein kinase kinase 2, beta
  • dog(486263) calcium/calmodulin-dependent protein kinase kinase 2, beta
  • cow(509084) calcium/calmodulin-dependent protein kinase kinase 2, beta
  • domestic cat(101097674) calcium/calmodulin-dependent protein kinase kinase 2, beta

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Antibodies

產品編號
描述
物種活性
應用
ANTI-MOUSE CAMKK2 (N-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
物種活性
mouse
應用
western blot
Anti-CAMKK2, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
物種活性
human
應用
western blot
Monoclonal Anti-CAMKK2 antibody produced in mouse, clone 1A11, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
immunoprecipitation (IP)

western blot