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Merck

BUB1

BUB1 mitotic checkpoint serine/threonine kinase

同義詞:
BUB1A, BUB1L, hBUB1
物種:
UniProtKB ID:
基因 ID:
  • Human(699) Summary: This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
  • Mouse(12235) budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)
  • Rat(296137) BUB1 mitotic checkpoint serine/threonine kinase
  • Zebrafish(100307076) BUB1 mitotic checkpoint serine/threonine kinase
  • fruit fly(33758) Bub1 homologue
  • cow(514777) budding uninhibited by benzimidazoles 1 homolog (yeast)
  • Horse(100064049) budding uninhibited by benzimidazoles 1 homolog (yeast)
  • domestic cat(101085035) budding uninhibited by benzimidazoles 1 homolog (yeast)
  • dog(100682599) budding uninhibited by benzimidazoles 1 homolog (yeast)
  • chicken(421226) budding uninhibited by benzimidazoles 1 homolog (yeast)
  • naked mole-rat(101724275) BUB1 mitotic checkpoint serine/threonine kinase
  • domestic guinea pig(100725012) BUB1 mitotic checkpoint serine/threonine kinase
  • sheep(101117404) budding uninhibited by benzimidazoles 1 homolog (yeast)
  • Domestic Rabbit(100352234) budding uninhibited by benzimidazoles 1 homolog (yeast)

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Antibodies

產品編號
描述
物種活性
應用
Anti-Bub1 Antibody, clone 14H5, clone 14H5, Chemicon®, from mouse,
物種活性
human, primate
應用
immunocytochemistry
immunoprecipitation (IP)

western blot