BLNK
B-cell linker
同義詞:
AGM4, BASH, BLNK-S, LY57, SLP-65, SLP65, bca
物種:
Human BLNK (29760), Mouse Blnk (17060), Rat Blnk (499356), Zebrafish blnk (405764), chicken BLNK (395733), dog BLNK (486814), cow BLNK (510393), Horse BLNK (100070841), domestic cat BLNK (101086423), naked mole-rat Blnk (101718500) ...更多
UniProtKB ID:
基因 ID:
- Human(29760) Summary: This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012]
- Mouse(17060) B cell linker
- Rat(499356) B-cell linker
- Zebrafish(405764) B-cell linker
- chicken(395733) B-cell linker
- dog(486814) B-cell linker
- cow(510393) B-cell linker
- Horse(100070841) B-cell linker
- domestic cat(101086423) B-cell linker
- naked mole-rat(101718500) B-cell linker
- domestic guinea pig(100712978) B-cell linker
- sheep(101111241) B-cell linker
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Antibodies
產品編號
描述
物種活性
應用
Anti-phospho-BLNK (pTyr96) antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot